1. Chemical Product and Manufacturer

A. Product Name: Propylene Glycol USP (PG USP).

• Recommended Use and Restrictions on Use
• Recommended Use: Medicines, cosmetics, food additives, essence/flavor.
• Restrictions on use: Prohibited for uses other than those specified above.

B. Manufacturer/Supplier/Distributor

C. Supplier: Phuong Nam Co.,Ltd

2. Hazards Risks

A. Classification of Hazards Risks

• PG USP is not a dangerous material per the OSHA Hazard Communication Definition.

B. Warning Sign, Including Caution

• Pictograph: No pictograph.
• Signal words: No signal words.
• Hazard Risk Words: No hazard/signal words.
• Precaution Words: No precaution words.

C. Other Hazards and Risks Not Included in the Hazard and Risk Classification (NFPA)

• Public Health: 0, Fire: 1, Reactivity: 0

3 Name and Contents of Ingredients

Substance Name: Propylene Glycol, Dipropylene Glycol, Others

Nickname (Usual Name) 1,2-Propanediol

CAS No. 57-55-6 -

Contents (%) Over 99.8 Under 0.2

4. First Aid Measures

A. Eye

• Irrigate eyes with a heavy stream of water for over 15 minutes.

B. Skin

• Wash clothing or shoes contaminated with a chemical substance before reuse.
• Take off clothing or shoes contaminated with a chemical substance, wash out the affected area with soap for over 15 minutes.
• Immediately wash with soapy water for over 15 minutes to remove chemical substances.

C. Inhalation

• If effects of exposure appear move the patient to a non-polluted area.
• If chemical is inhaled, consult with medical personnel immediately.

D. Ingestion

• If chemicals are ingested, consult with medical personnel.

E. First Aid and Doctor’s Caution: No data.

4. Fire Fighting and Explosion Measures

A. Suitable (Unsuitable) Fire Extinguishing Agents

• Suitable Fire Extinguishing Agents: CO2, powder fire extinguishing agent, carbon dioxide, water, ordinary foam, alcohol resistant foam.
• Unsuitable Fire Extinguishing Agents: No data.
• For Big Fires: Use alcohol resistant foam and a fine water spray.

B.Specific Hazards from Chemical Substances

• Pyrolysis Products: Carbon dioxide, carbon monoxide.
• Fire and Explosion risk: Slight risk of fire.

C.Protective Devices to Wear for Fire Extinguishing and Preventive Actions

• Move the case from near the fire if work can be done without risk.
• Spray high-pressure water on the leaked substance to prevent scattering.
• Construct a bank for further processing.
• Use a fire extinguisher that has been used and found effective for nearby fire.
• Avoid inhalation of substances or their fumes.
• Stand facing the wind and avoid low areas.

5.Measures for Accidental Spillages

A. Actions and Protective Devices Required Protecting the Body

• Workers should only stop a chemical spill if it is not dangerous to do so.

B.Actions for the Protection of the Environment

• Air: No data.
• Soil: No data.
• Water: No data.

C. Purification or Removal Method

Small Spills

• For further disposal, move the leaked substance to a suitable case and dispose.

Absorb using nonflammable substances.

Quarantine the exposed area and restrict access to the area except for the related personnel.

• Big Spills: No data.

6. Handling and Storage

A Tips for Safe Handling

• Store in an enclosed case.
• Ventilate using an overall or local air exhauster.
• Wash the body and clothing after using chemicals.

B. Safe Storage

• Store in an enclosed case.
• Store in a cool and dry place.
• Avoid contact with moisture.
• Avoid contact with halogens and intermediate halogens.
• Store and use in accordance with the laws and regulations of the relevant government department and local self-governing bodies.
• Store in well-ventilated areas.

7. Prevention of Exposure and Personal Protective Devices

A. Exposure Standard of Chemicals, Biological Exposure Criteria

• Domestic Regulations: No data.
• ACGIH Regulations: No data.
• Biological Exposure Criteria: No data.

B.Suitable Engineering Management

• Check whether the work process complies with the allowable standards and exposure standards of the Ministry of Labor.
• Install a ventilation device, such as a local exhauster, to ensure a suitable control wind speed.

C. Personal Protective Devices

• Protection of Respiratory Organs

Make sure to wear protection devices certified by KOSHA.

• Eye Protection

Install an emergency shower and basins for easy use by workers.

Wear protective glasses to protect the eyes from scattering substances.

• Eye Protection

Wear chemical resistant gloves to avoid the direct contact of water and chemicals.

• Body Protection

Wear chemical resistant protective wear to protect the skin.

8. Physical/Chemical Characteristics

A Appearance

Physical Properties: Liquid.

Color: Achromatic.

B Smell: Odorless.

C Detection Threshold: No data.

D Melting Point/Freezing Point : -60 ℃.

E Initial Boiling Point and Range of Boiling Point: 186 ~ 189 ℃.

F Steam Pressure: 0.08 ㎜ Hg (at 25 ℃).

G Solubility: 1,000 g/㎖.

H Steam Density: 2.6-2.62.

I Specific Gravity: 1.0361.

J n-Octanol/Water Partition Coefficient: -1.4.

K Viscosity: 58.1 cP (20℃).

L Molecular Weight: 76.09.

9 Stability and Reactivity

A Chemical Stability: Stable at room temperature and normal pressure.

B Possibility of hazardous reaction: No polymerization.

C Conditions to Avoid

• Avoid heat, flames, sparks and other sources of ignition. Avoid contact with substances that are prohibited for mixing.

D Substances to Avoid

• Acids, bases, combustible substances, halogen carbon chemicals, metals, metallic salts, oxidizers, reducers.

E Hazardous Substances Created at the Time of Decomposition

• Pyrolysis products or burning products: Carbon oxide.

10 Information on Toxicity

A Information on Route of Highly Likely Exposure

• Respiratory Organ: No data.
• Oral: No data.
• Skin Contact: No data.
• Eye Contact: No data.

B Delay by Short-term and Long-term Exposure, Acute Effects and Chronic Effects

• Acute Toxicity

Oral: LD50 2000 ㎎/㎏ rat (Classification 4 by the Ministry of Labor).

Percutaneous: LD50 > 16000 ㎎/㎏ rabbit.

Inhalation: No data.

• Skin Corrosion or Stimulation

Rabbit/OECD Guide-line 404: No irritation.

Human/Skin (104 mg/2D): Moderate irritation.

Male/Skin (10%/2D): Moderate irritation.

Children/Skin (30%/96H): Moderate irritation.

• Severe Eye Damage or Irritation

Human/Eye: Weak irritation.

Rabbit/Eye(100 mg): Minor irritation.

• Hypersensitivity of Respiratory Organ: No data.
• Skin Hypersensitivity: Human/Draize Test: No hypersensitivity.
• Carcinogenicity

IARC: No data.

NTP: No data.

OSHA: No data.

WISHA: No data.

ACGIH: No data.

• Mutagenesis of reproductive cells

In vitro - Salmonella typhimurium/TA 98, TA100, TA1535, TA1537 (Reverse Mutation Test; Ames Test): Negative; Human/sister chromatid exchange test: Negative.

• Reproductive Toxicity

If 1230 mg/kg is administered to a pregnant rabbit for 10 days as food, no effect on fertilization rate is observed together with no effect on the survival rate of the embryo or mother.

Skeletal system and teratogenesis are the biggest index for toxicity in the embryo and none in the mother. It is observed in mouse ≥500 mg/kg/day and rat ≥1,000 mg/kg/day. Effects on the weight and survival rate of the embryo occur at the higher densities.

• Target Organ• Whole Body Poisonous Substance (One Exposure)

Non-toxicity symptom is the restriction of central nerve if anesthetized. No organ to target.

• Target Organ• Whole Body Poisonous Substance (Repeated Exposure)

If exposed to rats for 90 days, weight and feed intake decreases, but no change is seen in the clinical-chemical and blood values. No toxic effects on organs (liver, kidney, pancreas and lung).

• Inhalation Toxicity: No data.

11 Effects on Environment

A Aquatic• Terrestrial Ecological Toxicity

• Fish: LC50 710 ㎎/ℓ 96 hr Oncorhynchus mykiss.
• Crustacean: EC50 > 1000 ㎎/ℓ 48 hr Daphnia magna.
• Birds: EC50 > 1000 ㎎/ℓ 72 hr Selenastrum capricornutum.

B Residual Tendency and Resolvability

• Residual Tendency: log Kow -1.4.
• Resolvability: No data.

C Biological Condensability

• Condensability: BCF< 1.
• Biological Condensability: > 60 (%) 10 days.

D Soil Mobility: No data.

E Other Hazardous Effects: No data.

12 Cautions for Disposal

A Disposal Method

• Discard the contents and case according to the regulations if it is regulated in the Waste Management Act.

B Caution for Disposal

• Consider the caution indicated in the regulations if it is regulated in the Waste Management Act.

13 Information on Transportation

A UN No.: No information on the classification of the UN Transport of Hazardous Substances.

B Suitable Ship Name: N/A.

C Class of Risk at Transportation: N/A.

D Case Grade: N/A.

E Marine Pollutants: No data.

F Special Measures That a User Should Know with Regard to Transportation or Means of Transportation

• Emergency Measures for Fire: N/A.
• Emergency Measures for Leakage: N/A.

14 Legal Regulation Status

A Regulations of the Occupational Safety and Health Acts: No data.

B Regulations of the Hazardous Chemical Management Act: No data.

C Regulations by the Hazardous Substance Safety Management Act: 4 Class 3 Petroleum (Soluble Liquid) 4000ℓ.

D Regulations by the Waste Management Act: No data.

E Regulations by Other Domestic and Foreign Acts

• Domestic Regulations

Residue-Prone Organic Pollutant Management Act: N/A.

• International Regulations

America Management Information (OSHA Regulations): N/A.

America Management Information (CERCLA Regulations): N/A.

America Management Information (EPCRA 302 Regulations): N/A.

America Management Information (EPCRA 304 Regulations): N/A.

America Management Information (EPCRA 313 Regulations): N/A.

America Management Information (Rotterdam Convention): N/A.

America Management Information (Stockholm Convention): N/A.

America Management Information (Montreal Protocol): N/A.

EU Classification Information (Fixed Classification): N/A.

EU Classification Information (Risk Words): N/A.

EU Classification Information (Safety Words): N/A.